Xem mã nguồn của Chymotrypsin-C

{{Infobox gene}}
'''Chymotrypsin C''', còn gọi là '''caldecrin''' hay '''elastase 4''' là [[enzyme]] ở người được mã hóa bởi [[gen]] ''CTRC''.<ref name="entrez">{{chú thích web | title = Entrez Gene: chymotrypsin C (caldecrin)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11330| access-date = }}</ref><ref name="pmid8635596">{{chú thích tạp chí |vauthors=Tomomura A, Akiyama M, Itoh H, Yoshino I, Tomomura M, Nishii Y, Noikura T, Saheki T | title = Molecular cloning and expression of human caldecrin | journal = FEBS Lett. | volume = 386 | issue = 1 | pages = 26–8 |date=May 1996 | pmid = 8635596 | doi = 10.1016/0014-5793(96)00377-8| url =https://archive.org/details/sim_febs-letters_1996-05-13_386_1/page/26}}</ref>

== Chức năng ==
Chymotrypsin C là thành viên của họ S1 [[peptidase]]. Protein mã hóa là một yếu tố hạ calci huyết thanh có hoạt tính [[protease]] giống [[chymotrypsin]].<ref name="entrez"/>

== Tham khảo ==
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== Đọc thêm ==
{{refbegin|2}}
*{{chú thích tạp chí  |vauthors=Freeman TC, Davies R, Calam J |title=Interactions of pancreatic secretory trypsin inhibitor in small intestinal juice: its hydrolysis and protection by intraluminal factors. |url=https://archive.org/details/sim_clinica-chimica-acta_1990-12-31_195_1-2/page/27 |journal=Clin. Chim. Acta |volume=195 |issue= 1–2 |pages= 27–39 |year= 1990 |pmid= 2093478 |doi=10.1016/0009-8981(90)90191-T  }}
*{{chú thích tạp chí  |vauthors=Masson E, Chen JM, Scotet V |title=Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis |journal=Hum. Genet. |volume=123 |issue= 1 |pages= 83–91 |year= 2008 |pmid= 18172691 |doi= 10.1007/s00439-007-0459-3 |display-authors=etal}}
*{{chú thích tạp chí  |vauthors=Rosendahl J, Witt H, Szmola R |title=Chymotrypsin C (CTRC) alterations that diminish activity or secretion are associated with chronic pancreatitis |journal=Nat. Genet. |volume=40 |issue= 1 |pages= 78–82 |year= 2008 |pmid= 18059268  |pmc=2650829 |doi= 10.1038/ng.2007.44 |display-authors=etal}}
*{{chú thích tạp chí  |vauthors=Kitahara K, Kawa S, Katsuyama Y |title=Microsatellite scan identifies new candidate genes for susceptibility to alcoholic chronic pancreatitis in Japanese patients |journal=Dis. Markers |volume=25 |issue= 3 |pages= 175–80 |year= 2008 |pmid= 19096130 |doi=  10.1155/2008/426764|display-authors=etal}}
*{{chú thích tạp chí  |vauthors=Stavridi ES, O'Malley K, Lukacs CM |title=Structural change in alpha-chymotrypsin induced by complexation with alpha 1-antichymotrypsin as seen by enhanced sensitivity to proteolysis |journal=Biochemistry |volume=35 |issue= 33 |pages= 10608–15 |year= 1996 |pmid= 8718849 |doi= 10.1021/bi9605806 |display-authors=etal}}
*{{chú thích tạp chí  |vauthors=Gregory SG, Barlow KF, McLay KE |title=The DNA sequence and biological annotation of human chromosome 1 |url=https://archive.org/details/sim_nature-uk_2006-05-18_441_7091/page/314 |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 |display-authors=etal}}
*{{chú thích tạp chí  |vauthors=Chang MC, Chang YT, Wei SC |title=Association of novel chymotrypsin C gene variations and haplotypes in patients with chronic pancreatitis in Chinese in Taiwan |journal=Pancreatology |volume=9 |issue= 3 |pages= 287–92 |year= 2009 |pmid= 19407484 |doi= 10.1159/000199437 |display-authors=etal}}
*{{chú thích tạp chí  |vauthors=Yoshino-Yasuda I, Kobayashi K, Akiyama M |title=Caldecrin is a novel-type serine protease expressed in pancreas, but its homologue, elastase IV, is an artifact during cloning derived from caldecrin gene |journal=J. Biochem. |volume=123 |issue= 3 |pages= 546–54 |year= 1998 |pmid= 9538241 |doi=  10.1093/oxfordjournals.jbchem.a021971|display-authors=etal}}
*{{chú thích tạp chí  |vauthors=Gerhard DS, Wagner L, Feingold EA |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334  |pmc=528928 |doi= 10.1101/gr.2596504 |display-authors=etal}}
*{{chú thích tạp chí  |vauthors=Harris WR, Malencik DA, Johnson CM |title=Purification and characterization of catalytic fragments of phosphorylase kinase gamma subunit missing a calmodulin-binding domain |url=https://archive.org/details/sim_journal-of-biological-chemistry_1990-07-15_265_20/page/11740 |journal=J. Biol. Chem. |volume=265 |issue= 20 |pages= 11740–5 |year= 1990 |pmid= 2365696 |doi=  |display-authors=etal}}
*{{chú thích tạp chí  |vauthors=Derikx MH, Szmola R, te Morsche RH |title=Tropical calcific pancreatitis and its association with CTRC and SPINK1 (p.N34S) variants |journal=Eur J Gastroenterol Hepatol |volume=21 |issue= 8 |pages= 889–94 |year= 2009 |pmid= 19404200 |doi= 10.1097/MEG.0b013e32832183cf |display-authors=etal}}
*{{chú thích tạp chí  |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |url=https://archive.org/details/sim_proceedings-of-the-national-academy-of-sciences-usa_2002-12-24_99_26/page/16899 |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932  |pmc=139241 |doi= 10.1073/pnas.242603899 |display-authors=etal}}
*{{chú thích tạp chí  |author1=Szmola R |author2=Sahin-Tóth M |title=Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: Identity with Rinderknecht's enzyme Y |url=https://archive.org/details/sim_proceedings-of-the-national-academy-of-sciences-usa_2007-07-03_104_27/page/11227 |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=104 |issue= 27 |pages= 11227–32 |year= 2007 |pmid= 17592142  |pmc=2040881 |doi= 10.1073/pnas.0703714104 }}
*{{chú thích tạp chí  |vauthors=Brecher AS, Yang MP |title=Acetaldehyde inhibits chymotrypsin and serum anti-chymotrypsin activity |journal=J. Investig. Med. |volume=46 |issue= 4 |pages= 146–52 |year= 1998 |pmid= 9635374 |doi=  }}
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[[Thể loại:Enzyme]]
[[Thể loại:Gen theo nhiễm sắc thể ở người]]


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