https://wikibeta.org/index.php?action=history&feed=atom&title=CLSTN1 CLSTN1 - Lịch sử thay đổi 2026-08-10T17:27:19Z Lịch sử thay đổi trang này trên wiki MediaWiki 1.46.0 https://wikibeta.org/index.php?title=CLSTN1&diff=6834219&oldid=prev imported>InternetArchiveBot: Add 2 books for Wikipedia:Thông tin kiểm chứng được (20260723sim)) #IABot (v2.0.9.5) (GreenC bot 2026-07-24T09:55:15Z <p>Add 2 books for <a href="/wiki/Wikipedia:Th%C3%B4ng_tin_ki%E1%BB%83m_ch%E1%BB%A9ng_%C4%91%C6%B0%E1%BB%A3c" title="Wikipedia:Thông tin kiểm chứng được">Wikipedia:Thông tin kiểm chứng được</a> (20260723sim)) #IABot (v2.0.9.5) (<a href="/wiki/Th%C3%A0nh_vi%C3%AAn:GreenC_bot" title="Thành viên:GreenC bot">GreenC bot</a></p> <p><b>Trang mới</b></p><div>{{Infobox gene}}<br /> &#039;&#039;&#039;[[Calsyntenin]]-1&#039;&#039;&#039; là [[protein]] ở người được mã hóa bởi [[gen]] &#039;&#039;CLSTN1&#039;&#039;.&lt;ref name=&quot;pmid10048485&quot;&gt;{{chú thích tạp chí | vauthors = Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Research | volume = 5 | issue = 6 | pages = 355–64 | date = Dec 1998 | pmid = 10048485 | pmc = | doi = 10.1093/dnares/5.6.355 }}&lt;/ref&gt;&lt;ref name=&quot;entrez&quot;&gt;{{chú thích web | title = Entrez Gene: CLSTN1 calsyntenin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&amp;Cmd=ShowDetailView&amp;TermToSearch=22883| access-date = }}&lt;/ref&gt;<br /> <br /> == Ý nghĩa lâm sàng ==<br /> Đột biến trên gen CLSTN1 thể hiện sự tương quan với cơ chế phát [[bệnh Alzheimer]].&lt;ref name=&quot;doi.10.1093/hmg/dds109&quot;&gt;{{chú thích tạp chí | vauthors = Vagnoni A, Perkinton MS, Gray EH, Francis PT, Noble W, Miller CC | title = Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production | journal = Human Molecular Genetics | volume = 21 | issue = 13 | pages = 2845–54 | date = Jul 2012 | pmid = 22434822 | doi = 10.1093/hmg/dds109 | pmc=3373235}}&lt;/ref&gt;<br /> <br /> == Tương tác ==<br /> CLSTN1 có khả năng [[Tương tác protein-protein|tương tác]] với [[APBA2]]&lt;ref name=pmid12972431&gt;{{chú thích tạp chí | vauthors = Araki Y, Tomita S, Yamaguchi H, Miyagi N, Sumioka A, Kirino Y, Suzuki T | title = Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism | url = https://archive.org/details/sim_journal-of-biological-chemistry_2003-12-05_278_49/page/49448 | journal = The Journal of Biological Chemistry | volume = 278 | issue = 49 | pages = 49448–58 | date = Dec 2003 | pmid = 12972431 | doi = 10.1074/jbc.M306024200 }}&lt;/ref&gt;&lt;ref name=pmid15037614&gt;{{chú thích tạp chí | vauthors = Araki Y, Miyagi N, Kato N, Yoshida T, Wada S, Nishimura M, Komano H, Yamamoto T, De Strooper B, Yamamoto K, Suzuki T | title = Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation | url = https://archive.org/details/sim_journal-of-biological-chemistry_2004-06-04_279_23/page/24342 | journal = The Journal of Biological Chemistry | volume = 279 | issue = 23 | pages = 24343–54 | date = Jun 2004 | pmid = 15037614 | doi = 10.1074/jbc.M401925200 }}&lt;/ref&gt; và [[protein tiền chất tinh bột]] (amyloid precursor protein).&lt;ref name=pmid12972431/&gt;&lt;ref name=pmid15037614/&gt;<br /> <br /> == Tham khảo ==<br /> {{tham khảo}}<br /> <br /> ==Liên kết ngoài==<br /> * {{UCSC gene info|CLSTN1}}<br /> * {{UCSC gene info|PIK3CD}}<br /> <br /> == Đọc thêm ==<br /> {{refbegin|2}}<br /> * {{chú thích tạp chí | vauthors = Konecna A, Frischknecht R, Kinter J, Ludwig A, Steuble M, Meskenaite V, Indermühle M, Engel M, Cen C, Mateos JM, Streit P, Sonderegger P | title = Calsyntenin-1 docks vesicular cargo to kinesin-1 | journal = Molecular Biology of the Cell | volume = 17 | issue = 8 | pages = 3651–63 | date = Aug 2006 | pmid = 16760430 | pmc = 1525238 | doi = 10.1091/mbc.E06-02-0112 }}<br /> * {{chú thích tạp chí | vauthors = Schmitt-Ulms G, Hansen K, Liu J, Cowdrey C, Yang J, DeArmond SJ, Cohen FE, Prusiner SB, Baldwin MA | title = Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues | url = https://archive.org/details/sim_nature-biotechnology_2004-06_22_6/page/724 | journal = Nature Biotechnology | volume = 22 | issue = 6 | pages = 724–31 | date = Jun 2004 | pmid = 15146195 | doi = 10.1038/nbt969 }}<br /> * {{chú thích tạp chí | vauthors = Araki Y, Miyagi N, Kato N, Yoshida T, Wada S, Nishimura M, Komano H, Yamamoto T, De Strooper B, Yamamoto K, Suzuki T | title = Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation | url = https://archive.org/details/sim_journal-of-biological-chemistry_2004-06-04_279_23/page/24342 | journal = The Journal of Biological Chemistry | volume = 279 | issue = 23 | pages = 24343–54 | date = Jun 2004 | pmid = 15037614 | doi = 10.1074/jbc.M401925200 }}<br /> * {{chú thích tạp chí | vauthors = Araki Y, Tomita S, Yamaguchi H, Miyagi N, Sumioka A, Kirino Y, Suzuki T | title = Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism | url = https://archive.org/details/sim_journal-of-biological-chemistry_2003-12-05_278_49/page/49448 | journal = The Journal of Biological Chemistry | volume = 278 | issue = 49 | pages = 49448–58 | date = Dec 2003 | pmid = 12972431 | doi = 10.1074/jbc.M306024200 }}<br /> * {{chú thích tạp chí | vauthors = Nakayama M, Kikuno R, Ohara O | title = Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs | journal = Genome Research | volume = 12 | issue = 11 | pages = 1773–84 | date = Nov 2002 | pmid = 12421765 | pmc = 187542 | doi = 10.1101/gr.406902 }}<br /> * {{chú thích tạp chí | vauthors = Vogt L, Schrimpf SP, Meskenaite V, Frischknecht R, Kinter J, Leone DP, Ziegler U, Sonderegger P | title = Calsyntenin-1, a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain | journal = Molecular and Cellular Neurosciences | volume = 17 | issue = 1 | pages = 151–66 | date = Jan 2001 | pmid = 11161476 | doi = 10.1006/mcne.2000.0937 }}<br /> * {{chú thích tạp chí | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5&#039;-end-enriched cDNA library | url = https://archive.org/details/sim_gene_1997-10-24_200_1-2/page/149 | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | date = Oct 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}<br /> * {{chú thích tạp chí | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | url = https://archive.org/details/sim_gene_1994-01-28_138_1-2/page/171 | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | date = Jan 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}<br /> {{refend}}<br /> <br /> [[Thể loại:Protein người]]<br /> [[Thể loại:Gen theo nhiễm sắc thể ở người]]<br /> [[Thể loại:Gen trên nhiễm sắc thể 1 ở người]]<br /> <br /> <br /> {{gene-1-stub}}</div> imported>InternetArchiveBot